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Growth inhibition of rats fed navy bean fractions

By: Contributor(s): Material type: ArticleArticleLanguage: English Description: 13(5):450-452Subject(s): LOC classification:
  • 10171
In: Journal of Agricultural and Food ChemistrySummary: Se encontro que 5 fracciones aisladas del frijol blanco crudo inhibian el crecimiento de las ratas. La fraccion 4 fue el principal inhibidor del crecimiento. El efecto inhibitorio del crecimiento de la fraccion 3 y posiblemente de las fracciones 1 y 2 en ratas podria atribuirse a la actividad inhibidora de tripsina. Se discute la posibilidad de la presencia de un factor toxico distinto a la hemaglutinina y/o el inhibidor tripsina en el frijol blanco. (RA-CIAT)Summary: Five fractions isolated from raw navy beans were found to inhibit growth of rats. Fraction 4 was the major growth-inhibiting fraction. The growth-inhibitory effect of fraction 3 and possibly of fractions 1 and 2 on rats could be attributed to trypsin- inhibitor activity. The possibility of the presence of a toxic factor other than hemagglutinin and/or trypsin inhibitor in navy beans is discussed. (AS)
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Se encontro que 5 fracciones aisladas del frijol blanco crudo inhibian el crecimiento de las ratas. La fraccion 4 fue el principal inhibidor del crecimiento. El efecto inhibitorio del crecimiento de la fraccion 3 y posiblemente de las fracciones 1 y 2 en ratas podria atribuirse a la actividad inhibidora de tripsina. Se discute la posibilidad de la presencia de un factor toxico distinto a la hemaglutinina y/o el inhibidor tripsina en el frijol blanco. (RA-CIAT) spa

Five fractions isolated from raw navy beans were found to inhibit growth of rats. Fraction 4 was the major growth-inhibiting fraction. The growth-inhibitory effect of fraction 3 and possibly of fractions 1 and 2 on rats could be attributed to trypsin- inhibitor activity. The possibility of the presence of a toxic factor other than hemagglutinin and/or trypsin inhibitor in navy beans is discussed. (AS) eng

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